Impact of whey protein phospholipid concentrate supplementation on steoporosis and sarcopenia

    PI: Gulustan Ozturk

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    Ozturk is an assistant professor of food science at UW–Madison who specializes in dairy food science. Her position is funded entirely by the Dairy Innovation Hub.

    As people age, they often lose muscle and bone strength, which can lead to frailty, poor mobility, and a higher risk of fractures—especially in postmenopausal women. Our research explores how a little-used dairy ingredient called whey protein phospholipid concentrate (WPPC) might help slow or prevent this decline. Early studies in young animals showed that WPPC could support bone growth, suggesting it may also help maintain strong bones and muscles later in life. This project will identify the key nutrients in WPPC, test their effects in both young and aging models, and explore how they might promote healthier aging. In doing so, we hope to uncover a new, value-added use for dairy byproducts that supports both human health and sustainability in the dairy industry.

    Upgrades and repairs to the Kemper C2200 mounted forage harvester for research plots

    PI: Gregg Sanford

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    Gregg Sanford is an assistant professor and Hub-funded faculty in the UW–Madison Department of Soil and Environmental Science. He traveled around the world growing up but spent each summer on his small family dairy farm in Viola, Wis. Sanford’s summer experiences growing up stuck with him, and after graduating from New College of Florida in 2002 with a B.A. in Biology (Field Botany) he turned his sights toward farming. His professional development has included private sector agricultural research in Florida, working on one of Wisconsin’s largest and most diversified organic vegetable farms, designing and implementing over 20 on-farm research trials, and more than a decade of experience with long-term, large-scale cropping systems experiments at the University of Wisconsin’s Research Stations.

    This project supports repairs and upgrades to a specialized piece of equipment, a Kemper C2200 forage harvester, which is used for research on small crop plots. The harvester helps collect and measure plant material, like corn silage, from different research areas where various treatments are being tested (such as manure application or soil amendments). These upgrades will improve the machine’s performance and accuracy, allowing researchers and students to better understand how different farming practices affect soil health and crop growth.

    Impact Assessment of Dairy Innovation Hub Activities

    PI: Charles Nicholson

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    Nicholson is an associate professor of animal and dairy sciences and agricultural and applied economics at UW–Madison who specializes in dairy economics. His research specialties include dairy markets and policy, food systems modeling, controlled-environment agriculture, and linkages between agriculture and food security. Nicholson’s position is funded by the Dairy Innovation Hub.

    The College of Agricultural and Life Sciences (CALS) and the Dairy Innovation Hub are interested in better understanding how the Hub’s research and outreach efforts are making a difference. The Dairy Innovation Hub, with its detailed records and broad range of projects, offers a great starting point for this kind of evaluation. Ultimately, this effort will help CALS better communicate the value of its work and ensure that research and outreach efforts are making a meaningful difference for Wisconsin’s dairy industry and beyond.

    Reducing nitrate leaching from dairy manure in corn silage systems

    PI: Xia Zhu-Barker

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    Zhu-Barker is an assistant professor of soil science at UW–Madison. Her research aims to improve the performance of agroecosystems by integrating biogeochemical, ecological, environmental, agronomic, economic, and social knowledge into the food, energy, and water aspects of management decisions. Zhu-Barker’s position is funded by the Dairy Innovation Hub.

    One of the biggest concerns in dairy farming is nitrogen pollution, which can harm both the environment and public health, especially when nitrogen from manure seeps into groundwater. This project looks at how changing when and how manure is applied to fields could reduce that risk.

    In Wisconsin, farmers often apply manure in the fall, but this timing doesn’t always benefit the growing crop and can lead to nitrogen loss through leaching, especially during winter and spring rains. This research will explore whether applying manure in the spring, or planting cover crops in the fall, can help keep nitrogen in the soil where crops can use it, instead of letting it wash away into water supplies. To do this, the research team will monitor how nitrogen moves through the soil under different farming practices using advanced tools like soil sensors and lab testing. Their goal is to better understand how manure nutrients behave in the soil and how much is actually available for crops to use.

    Förster-Technik CalfRail System

    PI: Lautaro Rostoll Cangiano

    Rostoll Cangiano is an assistant professor of animal and dairy sciences at UW–Madison. His research focuses on dairy cattle immunology and host pathogen interactions for improving animal health and welfare. Rostoll Cangiano’s position is funded by the Dairy Innovation Hub.

    The Förster-Technik CalfRail System is an automated feeding system that helps farmers care for their calves more efficiently. It works by moving a milk feeder along a rail between pens, delivering warm, freshly mixed milk to each calf in small amounts throughout the day. This helps mimic how calves would naturally nurse, supporting healthier growth and better digestion. One CalfRail can feed up to 60 calves, and two units working together can feed as many as 120 calves. This technology makes it easier to ensure each calf gets the right amount of milk at the right time, without extra labor.

    Evaluating novel dietary strategies to enhance nitrogen utilization efficiency in dairy cows

    PI: Yun Jiang

    Yun Jiang is an Assistant Professor of Dairy Nutrition in the Department of Animal & Dairy Sciences at the University of Wisconsin-Madison. She earned both her M.S. and Ph.D. in Animal Science, with a specialization in ruminant nutrition, from the University of Florida. Jiang’s research program focuses on developing nutritional strategies to optimize ruminal fermentation and feed efficiency, reduce environmental impacts such as methane emission, and improve feed quality and safety in the dairy industry. She also has a strong interest in the use of probiotics and postbiotics in dairy nutrition.

    Graduate student (pictured above): Houhua Hu is a PhD student in animal and dairy science at UW–Madison and is mentored by Yun Jiang. His research focuses on reducing methane and nitrous oxide emissions from dairy manure. Originally from Shanghai, China, Hu earned his undergraduate degree in Animal Science and Agribusiness Management from Penn State and his master’s degree from the Ohio State University

    Microbial true protein (MTP), produced in a cow’s rumen, is a key protein source, but only about 80% is digestible in the small intestine. Improving this digestibility could enhance nitrogen efficiency and milk protein production. This project aims to identify natural compounds, such as lysozyme, essential oils, and enzymes, that break down microbial cell walls and improve protein absorption. By increasing MTP digestibility, researchers hope to boost milk protein yields and support more sustainable dairy nutrition practices.

    Sebastian Arriola Apelo

    Engineering beyond the brown midrib phenotype: Using tissue- and cell-type specific engineering to improve the agronomic traits of digestible brown midrib maize mutants

    PI: Rebecca Smith

    Rebecca Smith is an assistant professor of translational plant science for dairy sustainability in the Department of Plant and Agroecosystem Sciences and the Dairy Innovation Hub at the University of Wisconsin–Madison and a co-investigator in the Great Lakes Bioenergy Research Center (GLBRC). She is a trainer in the agronomy, agroecology and plant breeding and plant genetics (PBPG) programs.

    Graduate student (pictured above): Prior to joining Smith’s lab, Jane Wernow was a Research Specialist at the Wisconsin Crop Innovation Center. She began work specializing in hemp transformation and she currently served on the Maize Research and Development team. Wernow is pursuing a Ph.D. in Plant Breeding and Plant Genetics at UW–Madison, with a continued focus on the intersection of plant science and biotechnology.

    Brown midrib (bm) maize mutants are known for their improved forage digestibility, but they often suffer from poor plant growth, limiting their use on farms. This project aims to genetically enhance bm maize by restoring key cell wall traits only where they are needed, supporting healthy growth while keeping the digestibility benefits. Researchers will also explore ways to increase specific root polymers to boost carbon sequestration. The result will be improved maize varieties that offer both nutritional value and environmental benefits for Wisconsin dairy producers.

    The antimicrobial dilemma: Exploring the effects of prophylactic antimicrobials on microbial colonization and immune development in dairy calves

    PI: Lautaro Rostoll Cangiano

    Rostoll Cangiano is an assistant professor of animal and dairy sciences at UW–Madison. His research focuses on dairy cattle immunology and host pathogen interactions for improving animal health and welfare. Rostoll Cangiano’s position is funded by the Dairy Innovation Hub.

    Graduate student (pictured above): Trinidad Fernandez Wallace is pursuing a master’s of science in dairy science and is mentored by Lautaro Rostoll Cangiano. She earned her bachelor of science in agricultural engineering from National University of Cordoba in Argentina. Her research seeks to understand immune changes and adaptations during the periparturient period of dairy cows and how this contributes to disease susceptibility.

    The preweaning period is one of the most vulnerable stages in a dairy calf’s life, with high rates of illness and death still common across North America. While antibiotics have traditionally been used to prevent disease during this time, growing concerns about antibiotic resistance and limited effectiveness have highlighted the need for better solutions. Early antibiotic use has been shown in other species to disrupt gut development and immune function. Similar effects may occur in calves, but more research is needed to understand how these treatments impact gut health and immunity in young dairy animals.

    Hilario Mantovani

    Fluidized bed drying (FBD) vs. spray drying (SD) of liquid whey protein phospholipid concentrate (WPPC): oxidate self-life, in-vitro digestion, and therapeutic potential

    PI: Mark Richards

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    Richards is a professor at UW–Madison and studies oxidative processes in proteins, with a focus on hemoglobin and myoglobin across different species. His research uses techniques like site-directed mutagenesis and protein crystallography to understand how structural differences influence oxidation, heme stability, and vitamin E metabolism. This work helps identify key protein sites that affect function and stability in mammals, birds, and fish.

    Graduate student (pictured above): Xin Qing is pursuing her Ph.D. in nutritional sciences at UW-Madison. She is a research assistant in the Department of Dairy and Animal Sciences and is mentored by Mark Richards. In addition to her education, she also has experience as a scientific graphical designer.

    Whey Protein Phospholipid Concentrate (WPPC) is prone to oxidation during processing and storage, which reduces its quality and value. This project explores a new fluidized bed drying (FBD) method that shows promise in reducing oxidation and improving protein digestibility compared to traditional spray drying (SD). In collaboration with Wisconsin-based AbE Manufacturing, researchers aim to produce higher-quality WPPC with extended shelf life, better nutritional benefits, and potential therapeutic applications for metabolic health.

    Vanessa Leone

    Assessing the functionality of a promising new dairy ingredient (WPPC) on the health of post-menopausal women

    PI: Bradley Bolling

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    Bolling is an associate professor of food science at UW–Madison. His research interests include food chemistry and analysis, dietary phytochemicals, functional foods and prevention of chronic disease.

    Graduate student (pictured above): Kevin Shih is pursuing a Ph.D. in nutrition and metabolism and is mentored by Bradley Bolling. Shih earned his MPH in public health nutrition dietetics from the University of North Carolina and Chapel Hill. In addition to his nutrition education, he also has experience in food biochemistry.

    Whey protein phospholipid concentrate (WPPC), a byproduct of whey protein production, is often discarded or used as animal feed, despite being rich in valuable nutrients like choline. This project aims to evaluate the nutritional benefits and safety of WPPC in postmenopausal women, a group at high risk for choline deficiency. Researchers will assess how well the body absorbs choline from WPPC and monitor potential health impacts, with the goal of transforming this underused byproduct into a valuable, sustainable human food ingredient.

    Gulustan Ozturk