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    Enhancing health: development of bioactive peptide-enriched string mozzarella cheese to combat hypertension in postmenopausal women

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    This project is developing a string mozzarella cheese enriched with bioactive peptides derived from whey protein phospholipid concentrate (WPPC), an underutilized dairy co-product. Researchers will produce and characterize the cheese and evaluate whether regular consumption can help lower blood pressure in postmenopausal women, a group at elevated risk for hypertension and cardiovascular disease. The project also seeks to identify new, health-promoting uses for WPPC and other dairy ingredients.

    The research could benefit consumers by providing a food-based approach to supporting heart health and healthy aging. For dairy processors and cheesemakers, it may create opportunities to develop premium, value-added cheeses with documented health benefits. By finding higher-value uses for WPPC, the project could also increase the value of milk processing streams, strengthening profitability and sustainability throughout Wisconsin’s dairy sector, including benefits for dairy farmers who supply the milk used in these products.

    Principal Investigator: Gulustan Ozturk

    Gulustan Ozturk is an Assistant Professor and Dairy Innovation Hub faculty member in the Department of Food and Nutritional Sciences at UW–Madison. Her research focuses on identifying, isolating, and utilizing bioactive compounds from milk and dairy streams to improve human health and nutrition. Ozturk specializes in dairy processing, membrane filtration technologies, and the development of value-added ingredients from underutilized dairy co-products, particularly whey protein phospholipid concentrate (WPPC). Through collaborations with industry and academic partners, her work aims to create next-generation dairy foods that support healthy aging, cardiovascular health, and personalized nutrition while enhancing the sustainability and economic value of dairy production.

    gozturk@wisc.edu
    (608) 263-2012
    Website

    Co-Principal Investigator: Bradley Bolling

    Bradley W. Bolling is a Professor of food and nutritional sciences at UW–Madison. His research focuses on nutrition, bioactive food components, gastrointestinal health, and the role of functional foods in reducing chronic disease risk. Bolling studies how dairy products and other food-derived compounds influence inflammation, cardiovascular health, and the gut microbiome, with a particular interest in translating food science discoveries into practical health applications. Through collaborations spanning dairy science, nutrition, and clinical research, he works to develop evidence-based dietary strategies that improve human health while creating new opportunities for value-added food products.

    bwbolling@wisc.edu
    (608) 890-0212

    Trainee: Yu Hasegawa

    Yu Hasegawa is a postdoctoral researcher in the UW–Madison, working with Gulustan Ozturk on dairy-based nutrition and health research. She earned her Ph.D. in Food Science and Technology from UC Davis and has extensive experience in nutrition, microbiology, immunology, and multi-omics research. Hasegawa’s work focuses on understanding how dairy foods and bioactive food components influence immune function, metabolism, gut health, and chronic disease risk. Her research integrates laboratory, animal, and human studies to develop science-based nutritional strategies that promote healthy aging and improve health outcomes

    yhasegawa2@wisc.edu